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Surgery improves advanced breast cancer survival PDF Print Email
Surgical removal of primary tumors in patients with metastatic breast cancer was associated with a 40% reduction in mortality risk, according to the findings of a new retrospective study recently presented at the joint congress of the European Cancer Organisation and the European Society for Medical Oncology. Dutch researchers, at Jeroen Bosch Hospital in Den Bosch, the Netherlands, and colleagues, analyzed data from 728 patients with distant metastatic disease at initial presentation. Forty percent had surgical removal of the primary tumor. Median survival was longer in patients who had surgery (31 months) compared with those who did not (14 months). Also, the five-year survival rate was 24.5% in patients who had tumors surgically removed; whereas, it was 13.1% in patients who did not have surgery (after adjustment for variables, including age, period of diagnosis, T-classification, number of metastatic sites, comorbidity, use of loco-regional radiotherapy and use of systemic therapy). “The research we did and other studies conducted on this subject are retrospective; therefore, we need to perform a randomized controlled trial to give us a more definitive answer as to whether surgery of primary breast tumors in stage IV disease has any benefit for survival,” Jetske Ruiterkamp, who lead the research, said during a press conference.